Coverage by content domain
Lessons and questions are organized around the exam’s content areas so your preparation reflects the structure of the assessment.
Pass your exam—or get your money back. Explore the 240 Guarantee ↗
Praxis test alignment
240's Praxis Biology Content Knowledge study guide is built around the official exam framework so you can study what is actually tested. This page shows exactly how the guide maps to the real exam — SMR by SMR and competency by competency.
Based on a competency-by-competency review of the official framework and the lessons, practice questions, flashcards, videos, and study materials included in this guide.
Transparent coverage
Our curriculum team begins with the official test framework, identifies the knowledge and skills candidates are expected to demonstrate, and maps instruction and practice to those expectations.
Lessons and questions are organized around the exam’s content areas so your preparation reflects the structure of the assessment.
Every competency is marked covered, partially covered, or a gap, so you can see where the guide is strongest and where to add your own review.
Alignment records provide a maintainable source of truth when exam frameworks, names, or objectives are updated.
Certification test standards are broad, but the exam questions are very specific. Our team of curriculum experts uses the 240 Study Guide Creation Process to ensure the most aligned, specific content for your Praxis Biology Content Knowledge (5236) test — so you are not wasting time on broad subject review that may not show up on exam day.
Transparent coverage is a strength. We show where the guide is strong, where depth is partial, and where a gap has been identified so you can make an informed study decision.
5Domains
218Competencies reviewed
46%Test-aligned
85Covered
29Partially covered
104Gaps
This study guide is based on the current official exam framework. We review and update alignment whenever the official framework changes so candidates are always studying current, accurate material.
SMR I.A · Nature of Science0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Nature of scientific knowledge | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Experimental design, data collection, and analysis | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Laboratory procedures | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR I.B · Science, Engineering, Technology, Society, and the Environment0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Engineering design and the interdependence of science, engineering, and technology | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Impacts of science, technology, human activity, and natural phenomena on society and the environment | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Applications of science in public health, medicine, and agriculture | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR II.A · Basic biochemistry and metabolism of living organisms0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Chemical structures and properties of biologically important molecules | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Dependency of biological processes on chemical principles developmental and content domains | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Structure and function of enzymes and the factors that influence their activity | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Major biochemical pathways and energy flow within an organism | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR II.B · Structure and function of cells and the mechanisms of basic cellular processes0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Characteristics of living versus nonliving things | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Structure and function of cells and organelles | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. How cells maintain their internal environment and respond to external signals | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Eukaryotic cell division, the cell cycle, and regulation of the processes | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR III.A · Mechanisms of molecular biology and genetic transmission0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Structure of nucleic acids and chromosomes | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Transfer of genetic information | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Nature of mutations | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Laboratory techniques | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 5. Mendelian genetics | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 6. Non-Mendelian inheritance | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR III.B · Mechanisms of evolution as a consequence of genetic variation and factors affecting evolution0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Sources of genetic variation | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Mechanisms of evolution | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Evidence supporting evolution | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Models of evolution | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 5. Scientific explanations for the origin and early evolution of life on Earth | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 6. Factors that lead to the extinction of species | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR IV.A · Diversity of Life0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Biological classification of organisms | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Defining characteristics of viruses, eubacteria, archaea, protists, fungi, plants, and animals | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Organizational hierarchy | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Cell differentiation and specialization | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR IV.B · Animal Biology0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Characteristics of animals | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Structure and function of major human organ systems | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. How homeostasis is maintained in organisms | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Reproduction, development, and growth in organisms | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 5. Behavior | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR IV.C · Plant Biology0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Characteristics of plants | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. How plants obtain, transport, and store materials | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Reproduction, growth and development | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. How plants respond to the environment | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR V.A · Biosphere organization and factors affecting organism interactions and population size0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Hierarchical structure of the biosphere | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Relationships within and between species | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Relationships among reproductive strategies, demographics, and population growth | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 4. Influence of biotic and abiotic components on community structure | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 5. Human impacts on ecosystems | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
SMR V.B · Characteristics of biomes, energy flow in ecosystems, and major biogeochemical cycles0 questions · 0 materials · 0 cards · 0 videosCoverage gap identified
| Official competency | Matching 240 topics | Alignment | Qs | Mats | Cards | Vids | Notes |
|---|---|---|---|---|---|---|---|
| 1. Ecological succession | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 2. Types of biomes and energy flow in the biomes | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
| 3. Biogeochemical cycles, including biotic and abiotic components | None | Coverage gap identified | 0 | 0 | 0 | 0 | No matching topic found in the study guide. |
Every 240 study guide starts with the official exam framework. From there, we organize lessons, practice, and study tools around the categories the exam uses to measure candidate knowledge.
We begin with the standards, domains, competencies, objectives, or content categories published by the testing authority.
We map every major area the exam is designed to cover so the guide reflects the real structure of the test.
We create study materials to support the official blueprint, not broad filler content.
We review practice content against the framework and real exam patterns so preparation stays targeted.
When official frameworks change, we review guides and update alignment as needed.
Reviewed by subject-matter experts and maintained to reflect current standards.
Not all study guides are built the same way. Here is what separates a test-aligned guide from a generic one — and why it matters when you are preparing for the Praxis Biology Content Knowledge.
The questions teacher candidates ask us most often about the Praxis Biology Content Knowledge study guide.
240 is a strong option because the guide is built around the official exam framework and shows detailed alignment by SMR and competency.
This guide is 46% aligned based on a competency-by-competency review of the official framework and the study resources included in the guide.
This page shows coverage transparently across covered, partially covered, and identified gaps so candidates can see exactly how the guide maps to the exam.
Partially covered means the guide addresses the core parts of a competency, but some depth or subtopics may still be limited.
Start with your exam
Accessibility